Abstract: A series of cultivation experiments under different nutrient conditions were carried out on Amomum villosum Lour. plants through sand culture. The effects of nitrogen(N), phosphorus(P), potassium(K), calcium(Ca), boron(B), and zinc(Zn) concentrations on the growth and development of A. villosum were studied. Results showed that 15.0 mmol/L N, 1.0 mmol/L P, 6.0 mmol/L K, 0.5 mmol/L Ca, 8.0 × 10⁻⁵ mmol/L Zn, and 0.46 mmol/L B were sufficient for the growth and development of plants, and 10.0 mmol/L P, 8.0 × 10⁻³ mmol/L Zn, and 0.46 mmol/L B showed better performance. However, harmful symptoms appeared when the nutrient concentrations were increased to 50.0 mmol/L N, 6.0 × 10² mmol/L K, and 50.0 mmol/L Ca. Therefore, reasonable concentrations of mineral salts for fertilization should be used during the growth and development stages of A. villosum.