Abstract: Flowering is a key qualitative change process in plant development, which is the transition from the vegetative growth to the reproductive growth stage. For ornamental plants, the time of flowering determines their market application and economic value. Plant flowering is complexly regulated by internal and external signals. Studies based on the model plant Arabidopsis thaliana have clarified six main flowering regulation pathways, which are independent of each other and intersect with each other, forming a complex genetic regulatory network. Chrysanthemum morifolium, a famous flower originating from China, is an important part of the world flower market. However, its characteristics of typical short-day not only increase the cost of flowering control in production, but also limit its application scope. Based on flowering regulation network of higher plants, this study reviewed the research progress on the genetic regulation mechanism of chrysanthemum flowering, in order to provide theoretical guidance for breeding work on the improvement of flowering time, and provide new insights for analyzing the flowering mechanism of higher plants.