Abstract: Based on four years of continuous detection on the concentration of tetrahydropalmatine,heavy metal and pesticide residue,we evaluated the active ingredient and security of Rhizoma Corydalis cultivated by Good Agricultural Practice in red-soil slopes in Jiangxi pro-vince.The results showed that tetrahydropalmatine detected by using HPLC was between 0.066%-0.088%,while harmful elements such as Pb(0.76 mg/kg),Cd(0.22 mg/kg),As(0.0025 mg/kg),Hg(0.007 mg/kg),and Cu(5.26 mg/kg)were detected by flame atomic absorption spectrophotometer,pesticide residue determined by gas chromatography showed organic chlorine was 0.033 mg/kg,and 2,2-bis(4-chlorophenyl)-1,1,1-trichloroethane and quintozene were only at trace concentrations.All content agreed with the request by the subdivision in Pharmacopoeia of the People Republic of China(2010)and the Green standards of medicinal plants and preparations for foreign trade and economy(WM/T2-2004).