寄主诱导的基因沉默在增强植物真菌病害抗性方面的研究进展

Research progress on host-induced gene silencing to promote plant resistance against fungal disease

摘要: 寄主诱导的基因沉默（host-induced gene silencing，HIGS）技术以RNAi技术为基础，可从反向遗传学角度研究基因功能，同时可创制具有持久抗性且稳定遗传的抗病品种，为增强植物抗病性提供了新的视角。本文阐明了HIGS技术的原理，总结了近年来该技术在增强植物真菌病害抗性方面最新的研究进展，分析了HIGS技术的优、缺点，并对HIGS技术的应用前景进行了展望。

Abstract: Host-induced gene silencing (HIGS) is a new technology based on RNA interference (RNAi). HIGS can identify gene functions from the view of reverse genetics and create disease resistant varieties with persistent resistance and stable inheritance. Thus, HIGS provides a new perspective for promoting plant disease resistance. In the current paper, we discuss the principles of HIGS technology, summarize the latest research progress in enhancing plant resistance against fungal diseases, and analyze the advantages and disadvantages of HIGS. Future prospects of HIGS technology are also discussed, with a focus on in-depth study of plant resistance.