Abstract: On the basis of investigation, collection and sifting, 162 species and varieties of macrofungi, which are traditional Chinese medicines, folk medicines and experimental anticancer, belonging to 35 families and 76 genera, are reported in the Dabie Mountain in Henan Province. They were 53 anticancer virtue and experimental anticancer macrofungi, 10 curative respiratory system macrofungi, 25 curative digestive system macrofungi, 6 curative mental macrofungi, 4 curative gynaecological macrofungi, 4 curative urological and endocrinological macrofungi, 54 curative traumatic and osteal macrofungi, 6 other virtues macrofungi. Finally, some reasonable suggestions are pointed out to the protection and exploitation resources of medicinal macrofungi in the Dabie Mountain.