Antioxidant activities and chemical constituents of roots of <i>Mondia whiteii</i> (Hook. f.) Skeels

Zhen Zhao-Meng; Zhuang Xiao-Cui; Liu Ye; Chen Gui-Lin; Guo Ming-Quan

doi:10.11913/PSJ.2095-0837.2020.40543

Plant Science Journal > 2020 > 38(4): 543-550. > DOI: 10.11913/PSJ.2095-0837.2020.40543 CSTR: 32231.14.PSJ.2095-0837.2020.40543

Zhen Zhao-Meng, Zhuang Xiao-Cui, Liu Ye, Chen Gui-Lin, Guo Ming-Quan. Antioxidant activities and chemical constituents of roots of Mondia whiteii (Hook. f.) Skeels[J]. Plant Science Journal, 2020, 38(4): 543-550. DOI: 10.11913/PSJ.2095-0837.2020.40543

Citation:

PDF (1335 KB)

Antioxidant activities and chemical constituents of roots of Mondia whiteii (Hook. f.) Skeels

Zhen Zhao-Meng^1,2,4,
Zhuang Xiao-Cui^1,2,4,
Liu Ye^1,2,3,
Chen Gui-Lin^1,2,3,
Guo Ming-Quan^1,2,3, ,

1. Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan 430074, China;
2. Sino-Africa Joint Research Center, Chinese Academy of Sciences, Wuhan 430074, China;
3. Innovation Academy for Drug Discovery and Development, Chinese Academy of Sciences, Shanghai 201203, China;
4. University of Chinese Academy of Sciences, Beijing 100049, China

Funds:

This work was supported by grants from the National Natural Science Foundation of China (81903791), Major Project for Special Technology Innovation of Hubei Province-Sino-Foreign Cooperation Project (2017AHB054), and Natural Science Foundation of Hubei Province (2019CFB254).

More Information

Received Date: November 29, 2019
Revised Date: January 11, 2020
Available Online: October 31, 2022
Published Date: August 27, 2020

Graphical Abstract

Abstract

Abstract

The antioxidant activities of different fractions of Mondia whiteii (Hook. f.) Skeels were measured by using three different assays (DPPH (1,1-diphenyl-2-picrylhydrazyl), ABTS(2,2'-azinobis-3-ethylbenzthiazoline-6-sulfonic acid) and FRAP (Ferric-Reducing Antioxidant Power), respectively). Total flavonoid and total phenol contents were also tested, and the chemical constituents of the dichloromethane fraction were further isolated and purified by AB-8 macroporous resin column chromatography (CC), Octadecylsilyl(ODSCC), Sephadex LH-20CC, and preparative-HPLC(High Performance Liquid Chromatography). Results showed that the dichloromethane fraction had the highest antioxidant activities and total phenol content. Furthermore, 10 compounds were obtained and identified, including 2-hydroxy-4-methoxybenzaldehyde(1), fraxetin(2), 7-metho-xycoumarin (3), α-hydroxypropiosyringone (4), ω-hydroxypropioguaiacone (5), cinnamic acid (6), salicylic acid (7), 4-methoxysalicylic acid (8), syringic acid (9), and azelaic acid (10). To the best of our knowledge, this study is the first to isolate compounds 3-10 from Mondia whiteii.
- Mondia whiteii,
- Antioxidant activities,
- Chemical constituents,
- Isolation

FullText(HTML)

References (34)

References

[1]	Venter HJT, Verhoeven RL, Bruyns PV. Morphology and taxonomy of Mondia (Apocynaceae:Periplocoideae)[J]. S Afr J Bot, 2009, 75(3):456-465.
[2]	郭肇凯, 张隆仁, 陈荣五, 廖俊旺. 新引进药用植物VUKA (Mondia whitei)对小鼠喂饲之安全性评估[J]. 台中区农业改良场研究学报, 2006(91):21-29. Guo ZK, Zhang LR, Chen RW, Liao JW. Safety evaluation of feeding a newly introduced medicinal plant VUKA (Mondia whitei) to mice[J]. Journal of Agricultural Improvement Field Research in Taizhong District, 2006(91):21-29.
[3]	Aremu AO, Cheesman L, Finnie JF, Staden JV. Mondia whitei (Apocynaceae):a review of its biological activities, conservation strategies and economic potential[J]. S Afr J Bot, 2011, 77(4):960-971.
[4]	Afanyibo YG, Esseh K, Idoh K, Koudouvo K, Agbonon A, Gbeassor M. Toxicity and antioxidant activity of Syzy-gium aromaticum, Mondia whitei, Carissa spinarum and Caesalpinia bonduc[J]. J Phytopharm, 2019, 8(3):124-128.
[5]	Gbadamosi I, Erinoso S. In vitro antioxidant and antimicrobial activities of Mondia whitei (Hook. f.) Skeels[J]. J Basic Appl Sci, 2015, 11:428-433.
[6]	Watcho P, Defo PBD, Wankeu-Nya M, Carro-Juarez M, Nguelefack TB, Kamanyi A. Mondia whitei (Periploca-ceae) prevents and Guibourtia tessmannii (Caesalpinia-ceae) facilitates fictive ejaculation in spinal male rats[J]. BMC Complementary Altern Med, 2013, 13(1):1-9.
[7]	Oketch-Rabah HA. Mondia whitei, a medicinal plant from Africa with aphrodisiac and antidepressant properties:a review[J]. J Diet Suppl, 2012, 9(4):272-284.
[8]	罗竣隆. Mondia whitei根部活性成分之探讨[D]. 台北:台北医学大学生药学研究所, 2009.
[9]	Gbadamosi IT, Aboaba SA. Essential oil constituents and in vitro antimicrobial activity of the root of Mondia whitei (Hook. f.) Skeels (Periplocaceae)[J]. J Pharmacogn Phytother, 2016, 8(8):163-167.
[10]	刘耕陶. 天然抗氧化剂与人类健康[J]. 中国科技信息, 2003(11):7-8. Liu GT. Natural antioxidants and human health[J]. China Science and Technology Information, 2003(11):7-8.
[11]	凌关庭. 抗氧化食品与健康[M]. 北京:化学工业出版社, 2004.
[12]	Chen GL, Fan MX, Wu JL, Li N, Guo MQ. Antioxidant and anti-inflammatory properties of flavonoids from lotus plumule[J]. Food Chem, 2019, 277:706-712.
[13]	Zhu MZ, Wu W, Jiao LL, Yang PF, Guo MQ. Analysis of flavonoids in lotus (Nelumbo nucifera) leaves and their antioxidant activity using macroporous resin chromatography coupled with LC-MS/MS and antioxidant biochemical assays[J]. Molecules, 2015, 20(6):10553-10565.
[14]	Xu YB, Chen GL, Guo MQ. Antioxidant and anti-Inflammatory activities of the crude extracts of Moringa oleifera from Kenya and their correlations with flavonoids[J]. Antioxidants, 2019, 8(8):296.
[15]	Garzón GA, Narv Na-Cuenca CE, Vincken JP, Gruppen H. Polyphenolic composition and antioxidant activity of açai (Euterpe oleracea Mart.) from Colombia[J]. Food Chem, 2017, 217:364-372.
[16]	Zou Y, Chang SK, Gu Y, Qian SY. Antioxidant activity and phenolic compositions of lentil (Lens culinaris var. Morton) extract and its fractions[J]. J Agr Food Chem, 2011, 59(6):2268-2276.
[17]	Mukonyi KW, Ndiege IO. 2-Hydroxy-4-methoxybenzaldehyde:Aromatic taste modifying compound from Mondia whytei Skeels[J]. Bull Chem Soc Ethiop, 2001, 15(2):137-141.
[18]	Okuyama E, Okamoto Y, Yamazaki M, Satake M. Pharmacologically active components of a peruvian medicinal plant, Huanarpo(Jatropha cilliata)[J]. ChemInform, 1996, 44(2):333-336.
[19]	李红亮, 李俊, 赵海清, 阿吉艾克拜尔艾萨. 新疆千叶蓍中化学成分及其抗氧化和抗菌活性研究[J]. 天然产物研究与开发, 2019, 31(1):125-131. Li HL, LI J, Zhao HQ, Ha AISA. Phytochemical, antioxidant and antibacterial activities of Achillea millefolium L.[J]. Natural Product Research and Development, 2019, 31(1):125-131.
[20]	崔泽旭, 徐嵬, 杨秀伟, 李伏君, 龚云, 等. 细叶十大功劳茎水提取物脂溶性部位的化学成分研究[J]. 中草药, 2018, 612(1):85-94. Cui ZX, Xu W, Yang XW, Li FJ, Gong Y, et al. Chemical constituents of lipophilic parts in water extract from stem of Mahonia fortunei[J]. Chinese Traditional and Herbal Drugs, 2018, 612(1):85-94.
[21]	杨佳倩, 贺文军, 谭宁华, 褚洪标, 张玉梅, 等. 头花马先蒿和管花马先蒿的化学成分[J]. 天然产物研究与开发, 2009(4):56-59. Yang JQ, He WJ, Tan NH, Chu HB, Zhang YM, et al. Chemical constituents of Pedicularis cephalantha Franch and P. siphonantha Don[J]. Natural Product Research and Development, 2009(4):56-59.
[22]	马学敏, 王力生, 郭亚健, 郭树仁. 活血益气汤中1个新的异黄酮类化合物[J]. 中国中药杂志, 2005(15):1159-1162. Ma XM, Wang LS, Guo YJ, Guo SR. A new isoflavone from Huoxue Yiqi Tang[J]. China Journal of Chinese Materia Medica, 2005(15):1159-1162.
[23]	Xin XL, Aisa HA, Wang HQ. Flavonoids and phenolic compounds from seeds of the Chinese plant Nigella glandulifera[J]. Chem Nat Compd, 2008, 44(3):368-369.
[24]	孟令杰, 刘百联, 张英, 周光雄. 地骨皮化学成分研究[J]. 中草药, 2014, 45(15):2139-2142. Meng LJ, Liu BL, Zhang Y, Zhou GX. Chemical consti-tuents from root bark of Lycium chinense[J]. Chinese Traditional and Herbal Drugs, 2014, 45(15):2139-2142.
[25]	Tian X, Guo S, He K, Roller M, Yang M, et al. Qualitative and quantitative analysis of chemical constituents of Ptychopetalum olacoides Benth[J]. Nat Prod Res, 2018, 32(3):354-357.
[26]	Kong LY, Li Y, Min ZD, Li X, Zhu TR. Coumarins from Peucedanum praeruptorum[J]. Phytochemistry, 1996, 41(5):1423-1426.
[27]	谢超. 神农香菊抗氧化活性及其应用研究[D]. 武汉:中医药大学, 2012.
[28]	朴香淑, 朴香兰, 洪承权, 刘同祥. 中药连翘体外抗氧化作用的研究[J]. 中央民族大学学报(自然科学版), 2008, 17(1):77-80. Pu XS, Pu XL, Hong CQ, Liu TX. Studies on antioxidantive activities from Forsythia suspense in vitro[J]. Journal of the Central University for Nationalities(Natural Science Edition), 2008, 17(1):77-80.
[29]	彭芍丹, 李积华, 黄晓兵, 静玮, 刘洋洋, 等. 菠萝蜜果皮不同萃取部位抗氧化活性的研究[J]. 食品工业科技, 2014, 35(20):82-85. Peng SD, Li JH, Huang XB, Jing W, Liu YY, et al. Study on antioxidant activties of different solvent extracts from jackfruit peel[J]. Science and Technology of Food Industry, 2014, 35(20):82-85.
[30]	曾桂凤, 肖红斌, 梁鑫淼. 一种丹参三七有效部位组合物及制备方法和用途:200510126487.9[P]. 2007-06-20.
[31]	Murthy KNC, Rajasekaran T, Giridhar P, Ravishanker GA. Antioxidant property of Decalepis hamiltonii Wight & Arn.[J]. Indian J Exp Biol, 2006, 44(10):832-837.
[32]	耿雪飞, 郑永杰, 赵明, UM Byunghun. 基于HPLC-ABTS体系筛选细叶杜香抗氧化活性成分[J]. 化学工程师, 2011(10):70-73. Geng XF, Zheng YJ, Zhao M, UM Byunghun. Screening of antioxidant components by HPLC-ABTS system in Ledum palustre L.[J]. Chemical Engineer, 2011(10):70-73.
[33]	马翠霞, 刘玉婷, 苗磊, 赵彧, 邵帅, 等. 黄花草木犀抗氧化活性成分研究[J]. 中国药学杂志, 2019, 54(19):1557-1564. Ma CX, Liu YT, Miao L, Zhao H, Shao S, et al. Solation, purification and identification of antioxidant compositions in Melilotus officinalis L.[J]. Chinese Pharmaceutical Journal, 2019, 54(19):1557-1564.
[34]	张雪, 续洁琨, 王乃利, 栗原博, 姚新生, 等. 金钗石斛中联苄类和酚酸类成分的抗氧化活性研究[J]. 中国药学杂志, 2008, 43(11):829-832. Zhang X, Xu JK, Wang NL, Li YB, Yao XS, et al. Studies on antioxidant activity of Bibenzyls and Phenolic components from Dendrobium nobile[J]. Chinese Pharmaceutical Journal, 2008, 43(11):829-832.

[1]	Zhang Cai-Fei, Peng Shuai, Tian Jing, Hu Guang-Wan, Wang Qing-Feng. A new species and a newly recorded species of Impatiens (Balsaminaceae) from Yunnan, China[J]. Plant Science Journal, 2020, 38(4): 437-447. DOI: 10.11913/PSJ.2095-0837.2020.40437
[2]	Liu Wen-Jian, Wang Li-Yan, Wu Lei, Jin Xiao-Hua. Crepidium josephianum, a new record of Orchidaceae from China[J]. Plant Science Journal, 2020, 38(3): 316-319. DOI: 10.11913/PSJ.2095-0837.2020.30316
[3]	Peng Shuai, Hu Guang-Wan, Cong Yi-Yan, Wang Qing-Feng. Impatiens dalaiensis, a newly recorded species of Impatiens from Yunnan, China[J]. Plant Science Journal, 2019, 37(5): 569-571. DOI: 10.11913/PSJ.2095-0837.2019.50569
[4]	LIU Qiang, LI Jian-Wu, YIN Jian-Tao, TAN Yun-Hong, WEN Bin, HUANG Wen, YE De-Ping. Agrostophyllum planicaule,A New Record of Orchidaceae from Yunnan,China[J]. Plant Science Journal, 2012, (3): 299-300. DOI: 10.3724/SP.J.1142.2012.30299
[5]	WANG Yi, WANG Yan. Habenaria anomaliflora,a New Record of Orchidaceae from China[J]. Plant Science Journal, 2010, 28(6): 696-697.
[6]	HU Sheng, LIU Guo-Xiang, ZHOU Guang-Jie, MEI Hong, HU Zheng-Yu. Peridinium polonicum,A New Record of Freshwater Toxic Dinoflagellate from China[J]. Plant Science Journal, 2008, 26(5): 454-457.
[7]	YOU Qing-Min, WANG Quan-Xi. New Records of Pinnularia(Bacillariophyta) from Xinjiang, China[J]. Plant Science Journal, 2007, 25(6): 572-575.
[8]	CHEN Shan, HU Hong-Jun. New Varieties and New Records of Green Flagellates from China(Ⅱ)[J]. Plant Science Journal, 2003, 21(6): 492-496.
[9]	CHEN Shan, HU Hong-Jun. New Species and Records of Green Flagellates from China[J]. Plant Science Journal, 2002, 20(3): 191-198.
[10]	Ma Jilong, LI Yanjun. NEW RECORD OF THE CAREX FROM CHINA[J]. Plant Science Journal, 1998, 16(1): 32-32.

Cited By

Cited by

Periodical cited type(8)

1.	师雪淇，程金花，管凝，侯芳，沈子雅. 喀斯特地区典型植被根系对优先流的影响. 水土保持研究. 2024(05): 73-83 .
2.	庞榆，贺同鑫，孙建飞，宁文彩，裴广廷，胡宝清，王斌. 北热带喀斯特森林优势树种细根生物量估算模型构建. 植物生态学报. 2024(10): 1312-1325 .
3.	覃桂丽，玉舒中. 降香黄檀根系性状对石灰岩石砾的适应响应. 西南林业大学学报(自然科学). 2023(03): 24-32 .
4.	吴静，盛茂银，肖海龙，郭超，王霖娇. 西南喀斯特石漠化环境适生植物细根构型及其与细根和根际土壤养分计量特征的相关性. 生态学报. 2022(02): 677-687 .
5.	林伟山，德科加，向雪梅，钱诗祎，魏希杰，冯廷旭. 天然草地植被-土壤系统碳、氮、磷(钾)库的时空分布格局研究进展. 青海畜牧兽医杂志. 2022(02): 45-51+68 .
6.	杨慧，宁静，马洋，周孟霞，曹建华. 西南岩溶区植被碳循环研究进展. 广西植物. 2022(06): 903-913 .
7.	薛建辉，周之栋，吴永波. 喀斯特石漠化山地退化土壤生态修复研究进展. 南京林业大学学报(自然科学版). 2022(06): 135-145 .
8.	张新生，卢杰. 根系生物量及其对根际生态系统响应的研究进展. 江苏农业科学. 2021(17): 39-45 .

Other cited types(9)

Get Citation

PDF

XML

Article views (609) PDF downloads (870) Cited by(17)

Turn off MathJax

Article Contents

Abstract

References

Antioxidant activities and chemical constituents of roots of Mondia whiteii (Hook. f.) Skeels

Abstract

References

Related Articles

Cited by

Periodical cited type(8)

Other cited types(9)

Catalog

Antioxidant activities and chemical constituents of roots of Mondia whiteii (Hook. f.) Skeels

Abstract

References

Related Articles

Cited by

Periodical cited type(8)

Other cited types(9)

Catalog

Export File

Citation

Format

Content